MSDS:Nitrous Oxide

MSDS

Part 1: Chemical Product and Company Identification

SUBSTANCE: NITROUS OXIDE

TRADE NAMES/SYNONYMS: DINITROGEN MONOXIDE; FACTITIOUS AIR; LAUGHING GAS; HYPONITROUS ACID ANHYDRIDE; NITROGEN (I) OXIDE; NITROGEN OXIDE; STCC 4904340; UN 1070; NITROGEN OXIDE (N2O); DINITROGEN OXIDE; NITROUS OXIDE, COMPRESSED; N2O; RTECS QX1350000

CHEMICAL FAMILY: inorganic, gas

COMPANY: PT ANEKA GAS INDUSTRI

Wisma 77 Lt.6 Jl. S. Parman Kav.77, Jakarta Barat 11410

PHONE: 62-21 53670071

Creation date: 12 December 2005

Part 2: Composition, Information on ingredients

COMPONENT: NITROUS OXIDE CAS NUMBER: 10024-97-2 EC NUMBER (EINECS): 233-032-0 PERCENTAGE: 100.0

Part 3: Hazards Identifications

NFPA RATINGS (SCALE 0-4): HEALTH=1 FIRE=0 REACTIVITY=0 EMERGENCY OVERVIEW: PHYSICAL DESCRIPTION: Colorless gas or liquid with a slightly sweet odor and taste. MAJOR HEALTH HAZARDS: potentially fatal if inhaled, central nervous system depression, difficulty breathing PHYSICAL HAZARDS: Containers may rupture or explode if exposed to heat. POTENTIAL HEALTH EFFECTS: INHALATION: SHORT TERM EXPOSURE: nausea, vomiting, symptoms of drunkenness, hyperactivity or drowsiness, hearing loss, suffocation, death LONG TERM EXPOSURE: tingling sensation, impotence, reproductive effects SKIN CONTACT: SHORT TERM EXPOSURE: blisters, frostbite LONG TERM EXPOSURE: no information is available EYE CONTACT: SHORT TERM EXPOSURE: frostbite, blurred vision LONG TERM EXPOSURE: no information is available INGESTION: SHORT TERM EXPOSURE: frostbite LONG TERM EXPOSURE: no information is available CARCINOGEN STATUS: OSHA: No NTP: No IARC: No

Part 4: First Aid Measures

INHALATION: If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. If breathing is difficult, oxygen should be administered by qualified personnel. Get immediate medical attention. SKIN CONTACT: If frostbite or freezing occur, immediately flush with plenty of lukewarm water (105-115 F; 41-46 C). DO NOT USE HOT WATER. If warm water is not available, gently wrap affected parts in blankets. Get immediate medical attention. EYE CONTACT: Flush eyes with plenty of water. INGESTION: If a large amount is swallowed, get medical attention. NOTE TO PHYSICIAN: For inhalation, consider oxygen

Part 5: Fire Fighting Measures

FIRE AND EXPLOSION HAZARDS: Negligible fire hazard. Containers may rupture or explode if exposed to heat. Gas/air mixtures are explosive. EXTINGUISHING MEDIA: carbon dioxide, regular dry chemical Large fires: Use regular foam or flood with fine water spray. FIRE FIGHTING: Move container from fire area if it can be done without risk. Cool containers with water spray until well after the fire is out. Stay away from the ends of tanks. For fires in cargo or storage area: Cool containers with water from unmanned hose holder or monitor nozzles until well after fire is out. If this is impossible then take the following precautions: Keep unnecessary people away, isolate hazard area and deny entry. Let the fire burn. Use extinguishing agents appropriate for surrounding fire. Cool containers with water spray until well after the fire is out. Apply water from a protected location or from a safe distance. Do not get water directly on material. Reduce vapors with water spray. Avoid inhalation of material or combustion by-products. Stay upwind and keep out of low areas. Consider downwind evacuation if material is leaking.

Part 6: Accidental Release Measures

OCCUPATIONAL RELEASE: Stop leak if possible without personal risk. Avoid contact with combustible materials. Keep unnecessary people away, isolate hazard area and deny entry. Ventilate closed spaces before entering.

Part 7: Handling and Storage

STORAGE: Cylinder temperature should not exceed 125 F (52 C). 29 CFR Subpart "H"-Hazardous Materials. National Fire Protection Association publication #55, "Standard for the Storage, Use and Handling of Compressed and Liquified Gases in Portable Cylinders". Compressed Gas Association publication P-1, "Safe Handling of Compressed Gases in Containers". Store and handle in accordance with current regulations and standards: OSHA 29 CFR 1910.101

Part 8: Exposure Controls, Personal Protection

EXPOSURE LIMITS: NITROUS OXIDE: 50 ppm ACGIH TWA 25 ppm (46 mg/m3) NIOSH recommended TWA (halogenated anesthetic gas) 180 mg/m3 (100 ml/m3) DFG MAK (peak limitation category-II, 1) 100 ppm (183 mg/m3) UK OES TWA MEASUREMENT METHOD: Gas collection bag; Infrared spectrometry; NIOSH IV # 6600 VENTILATION: Provide local exhaust ventilation system. Ensure compliance with applicable exposure limits. EYE PROTECTION: For the gas: Eye protection not required, but recommended. For the liquid: Wear splash resistant safety goggles. Contact lenses should not be worn. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. CLOTHING: For the gas: Protective clothing is not required. For the liquid: Wear appropriate protective, cold insulating clothing. GLOVES: Wear insulated gloves. RESPIRATOR: Under conditions of frequent use or heavy exposure, respiratory protection may be needed. Respiratory protection is ranked in order from minimum to maximum. Consider warning properties before use. Any supplied-air respirator with a full facepiece that is operated in a pressure-demand or other positive-pressure mode. Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. For Unknown Concentrations or Immediately Dangerous to Life or Health - Any supplied-air respirator with full facepiece and operated in a pressure-demand or other positive-pressure mode in combination with a separate escape supply. Any self-contained breathing apparatus with a full facepiece.

Part 9: Physical and Chemical Properties

PHYSICAL DESCRIPTION: Colorless gas or liquid with a slightly sweet odor and taste. MOLECULAR WEIGHT: 44.01 MOLECULAR FORMULA: N2-O BOILING POINT: -128 F (-89 C) FREEZING POINT: -132 F (-91 C) VAPOR PRESSURE: 760 mmHg @ -88 C VAPOR DENSITY (air=1): 1.530 SPECIFIC GRAVITY: Not applicable DENSITY: 1.8122 g/L @ 25 C WATER SOLUBILITY: 59% @ 25 C PH: Not applicable VOLATILITY: Not applicable ODOR THRESHOLD: Not available EVAPORATION RATE: Not applicable VISCOSITY: 0.0145 cP @ 25 C COEFFICIENT OF WATER/OIL DISTRIBUTION: Not applicable SOLVENT SOLUBILITY: Soluble: sulfuric acid, alcohol, alkali solutions, ether, oils

Part 10: Stability and Reactivity

REACTIVITY: Stable at normal temperatures and pressure. CONDITIONS TO AVOID: Avoid contact with combustible materials. Protect from physical damage and heat. Containers may rupture or explode if exposed to heat. INCOMPATIBILITIES: combustible materials, metals, bases, reducing agents, peroxides, metal salts, metal oxides NITROUS OXIDE: ACETYLENE: Forms explosive mixture. ALUMINUM: Oxidizes. AMMONIA: Forms explosive mixture. BORON (AMORPHOUS): Ignites when heated. CADMIUM: Oxidizes @ 300 C. CARBON MONOXIDE: Explosion hazard. COBALT: Oxidizes @ 200 C. COPPER: Oxidizes @ 150 C. DITUNGSTEN CARBIDE: Incandescent reaction. ETHANOL: Mixtures with supercritical nitrous oxide may detonate. HYDRAZINE: Ignites. HYDROGEN: Forms explosive mixture. HYDROGEN + OXYGEN: Ignition reaction with possible explosion. HYDROGEN SULFIDE: Forms explosive mixture. IRON: Oxidizes @ 170 C. LEAD: Oxidizes @ 300 C. LITHIUM HYDRIDE: Ignites. METHANOL: Mixtures with supercritical nitrous oxide may detonate. NICKEL: Oxidizes @ 200 C. OXIDIZABLE ORGANIC MATERIALS: Mixtures with supercritical nitrous oxide may detonate. ORGANIC PEROXIDES: Incompatable. PHENYLLITHIUM: Forms unstable products. PHOSPHINE: Explodes when sparked. REDUCING AGENTS (STRONG): Violent reaction @ room temperature. SODIUM (GASEOUS): Incandesces @ 260 C. STANNOUS CHLORIDE: Violent reaction. TIN (II) OXIDE: Ignites @ 400 C. TUNGSTEN CARBIDE: Ignites with incandescence @ 600 C. HAZARDOUS DECOMPOSITION: Thermal decomposition products: oxides of nitrogen POLYMERIZATION: Will not polymerize.

Part 11: Toxicological Information

NITROUS OXIDE: TOXICITY DATA: 24 mg/kg/2 hour(s) inhalation-human TCLo; 50 ppm/6 hour(s)-13 week(s) intermittent inhalation-mouse TCLo CARCINOGEN STATUS: IARC: Human Inadequate Evidence, Animal Inadequate Evidence, Group 3 (Anesthetics, volatile); ACGIH: A4 -Not Classifiable as a Human Carcinogen TARGET ORGANS: central nervous system MUTAGENIC DATA: sex chromosone loss and non disjunction - Drosophila melanogaster inhalation 99 pph 6 minute(s)-continuous; DNA inhibition - human inhalation 50 pph 24 hour(s); DNA inhibition - rat inhalation 75000 ppm 24 hour(s); other mutation test systems - rat inhalation 50 pph 24 hour(s) REPRODUCTIVE EFFECTS DATA: 5 pph inhalation-rat TCLo/4 hour(s) 6-15 day(s) pregnant female continuous; 20 pph inhalation-rat TCLo/8 hour(s) 28 day(s) male; 50 pph inhalation-rat TCLo/24 hour(s) 8-11 day(s) pregnant female continuous; 50 ppm inhalation-rat TCLo/6 hour(s) 30 day(s) male; 1 pph inhalation-rat TCLo/8 hour(s) 1-21 day(s) pregnant female continuous; 50 pph inhalation-rat TCLo/4 hour(s) 14 day(s) pregnant female continuous; 3 gm/kg subcutaneous-rat TDLo 8 day(s) pregnant female continuous; 3 gm/kg subcutaneous-rat TDLo 8 day(s) pregnant female continuous; 75 pph inhalation-mouse TCLo/6 hour(s) 14 day(s) pregnant female continuous; 5000 ppm inhalation-mouse TCLo/4 hour(s) 14 day(s) pregnant female continuous; 90 pph inhalation-hamster TCLo/24 hour(s) 10 day(s) pregnant female continuous; 95 pph inhalation-hamster TCLo/24 7 day(s) pregnant female continuous ADDITIONAL DATA: Central nervous system depressants may enhance the toxic effects. HEALTH EFFECTS: INHALATION: ACUTE EXPOSURE: NITROUS OXIDE: Inhalation of high concentrations without adequate oxygen can result in headache and serious anoxia causing fatal cardiac arrhythmias or brain damage with cerebral edema, permanent mental deficit, and visual system involvement. High concentrations mixed with air or oxygen may produce signs of central nervous system depression including drowsiness, lightheadedness, confusion, hysteria, anesthesia, and unconsciousness. Some persons may experience nausea, and occasionally vomiting, following anesthesia. Anesthetic concentrations may produce permanent hearing loss in persons who have had middle ear surgery. Exposure of pregnant rats to 75% nitrous oxide for 8 hours on the 15th day of gestation resulted in permanent alterations in neurobehavioral output of the newborns as exhibited by hyperactivity in males and hypoactivity in females. CHRONIC EXPOSURE: NITROUS OXIDE: Prolonged occupational exposure or abuse has resulted in neurologic effects including initial signs of numbness, paresthesias, and loss of pain and temperature sensation, progressing to muscle weakness, loss of balance, gait ataxia, Lhermitte's sign, impotence, sphincter difficulties, loss of bladder and vaginal sensation, and reduction in dexterity, cognition, and motor and audiovisual skills. Recovery may occur in months, but damage may be permanent. Signs of bone marrow depression including fatal aplastic anemia have been reported. There have also been increased incidences of kidney and liver disorders, spontaneous abortions, and fetal malformations reported among dentists and their assistants. Exposure to nitrous oxide in utero prior to organogenesis resulted in physical malformations in rat fetuses; permanent alterations in brain function can result following exposure during a period beyond major organogenesis. Prolonged exposure produced some damage to chromosomes in bone marrow cells and spermatogonial cells in male rats. 500 ppm 8 hrs/day/35 days disrupted hormonal cycles and decreased conception in female rats. SKIN CONTACT: ACUTE EXPOSURE: NITROUS OXIDE: No adverse effects have been reported from the gas. Due to rapid evaporation, the liquid may cause frostbite with redness, tingling, and pain or numbness. In more severe cases, the skin may become hard and white and blisters may form. CHRONIC EXPOSURE: NITROUS OXIDE: No data available. EYE CONTACT: ACUTE EXPOSURE: NITROUS OXIDE: No adverse effects have been reported from the gas. Due to rapid evaporation, the liquid may cause frostbite with redness, pain, and blurred vision. CHRONIC EXPOSURE: NITROUS OXIDE: No data available. INGESTION: ACUTE EXPOSURE: NITROUS OXIDE: If the liquid is swallowed, frostbite damage of the lips, mouth, and mucous membranes may occur. CHRONIC EXPOSURE: NITROUS OXIDE: No data available

Part 12: Ecological Information

Not available

Part 13: Disposal Consideration

Dispose in accordance with all applicable regulations. Part 14: Transport Information U.S. DOT 49 CFR 172.101: PROPER SHIPPING NAME: Nitrous oxide ID NUMBER: UN1070 HAZARD CLASS OR DIVISION: 2.2 LABELING REQUIREMENTS: Nonflammable gas; Oxidizer PACKAGING AUTHORIZATIONS: EXCEPTIONS: 49 CFR 173.306 NON-BULK PACKAGING: 49 CFR 173.304 BULK PACKAGING: 49 CFR 173.314, 315 QUANTITY LIMITATIONS: PASSENGER AIRCRAFT OR RAILCAR: 75 kg CARGO AIRCRAFT ONLY: 150 kg LAND TRANSPORT ADR/RID: SUBSTANCE NAME: Nitrous oxide (N2O)/Nitrous oxide UN NUMBER: UN1070 ADR/RID CLASS: 2 ITEM NUMBER: 5(a)/2O WARNING SIGN/LABEL: 2; 05/2; 05; 13 HAZARD ID NUMBER: 25 AIR TRANSPORT IATA/ICAO: PROPER SHIPPING NAME: Nitrous oxide, compressed UN/ID NUMBER: UN1070 IATA/ICAO CLASS: 2.2 SUBSIDIARY RISK: 5.1 LABEL: Nonflammable gas; Oxidizer MARITIME TRANSPORT IMDG: CORRECT TECHNICAL NAME: Nitrous oxide UN/ID NUMBER: UN1070 IMDG CLASS: 2(2.2) SUBSIDIARY RISK LABEL: Oxidizing agent EmS No.: 2-08 MFAG Table No.: none IMDG CODE PAGE: 2166

WE BELIEVE THE INFORMATION SOURCE IS RELIABLE AND THE INFORMATION IS ACCURATE AS OF THE DATE HEREOF, HOWEVER, ACCURACY OR COMPLETENESS IS NOT GUARANTEED AND NO WARRANTY OF ANY TYPE IS GRANTED.